Coenzyme A

CAS No. 85-61-0

Coenzyme A ( —— )

Catalog No. M22129 CAS No. 85-61-0

Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 32 In Stock
10MG 42 In Stock
25MG 68 In Stock
50MG 101 In Stock
100MG 149 In Stock
200MG 221 In Stock
500MG 374 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Coenzyme A
  • Note
    Research use only, not for human use.
  • Brief Description
    Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.
  • Description
    Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.Covalent binding of Coenzyme A to Peroxiredoxin 5 (Prdx5) results in complete inhibition of its peroxidase activity, which is reversed by reduction with DTT. Many human pathologies, including cancer, diabetes, and neurodegeneration, have been associated with abnormal biosynthesis and homeostasis of CoA and its derivatives.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    Cardiovascular system
  • Indication
    Hyperlipoproteinemia

Chemical Information

  • CAS Number
    85-61-0
  • Formula Weight
    767.53
  • Molecular Formula
    C21H36N7O16P3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bakovi? J, et al. A key metabolic integrator, coenzyme A, modulates the activity of peroxiredoxin 5 via covalent modification. Mol Cell Biochem. 2019 Aug 2.
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